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| Week | Date | Visitor | Score | @ | Home | Score |
| 01 | 11-Sep | Panthers | 21 | @ | Cardinals | 28 |
| 02 | 18-Sep | Packers | 30 | @ | Panthers | 23 |
| 03 | 25-Sep | Jaguars | 10 | @ | Panthers | 16 |
| 04 | 02-Oct | Panthers | 29 | @ | Bears | 34 |
| 05 | 09-Oct | Saints | 30 | @ | Panthers | 27 |
| 06 | 16-Oct | Panthers | 17 | @ | Falcons | 31 |
| 07 | 23-Oct | Redskins | 20 | @ | Panthers | 33 |
| 08 | 30-Oct | Vikings | 24 | @ | Panthers | 21 |
| 09 | Bye | |||||
| 10 | 13-Nov | Titans | 30 | @ | Panthers | 3 |
| 11 | 20-Nov | Panthers | 35 | @ | Lions | 49 |
| 12 | 27-Nov | Panthers | 27 | @ | Colts | 19 |
| 13 | 04-Dec | Panthers | 38 | @ | Buccaneers | 19 |
| 14 | 11-Dec | Falcons | 31 | @ | Panthers | 23 |
| 15 | 18-Dec | Panthers | 28 | @ | Texans | 13 |
| 16 | 24-Dec | Buccaneers | 16 | @ | Panthers | 48 |
| 17 | 01-Jan | Panthers | 17 | @ | Saints | 45 |
NFC SOUTH
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